Description: Squalene is a component of some adjuvants that are added to vaccines to enhance the immune response. MF59, an adjuvant produced by Novartis and added to the FLUAD flu vaccine, is such an example. Squalene by itself is not an adjuvant, but emulsions of squalene with surfactants do enhance the immune response.
Description: An adjuvant is an ingredient used in some vaccines that helps create a stronger immune response in people receiving the vaccine. In other words, adjuvants help vaccines work better. Some vaccines that are made from weakened or killed germs contain naturally occurring adjuvants and help the body produce a strong protective immune response.
Description: Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives. Yeast cells have been genetically engineered to produce commercially useful quantities of ...
Description: Squalene was an experimental toxic vaccine adjuvant added to vaccines around the time of the first Gulf War. Squalene has been implicated in GWS (Gulf War Syndrome) in this study , and the DoD (Department of Defense) conveniently “lost” (read destroyed) 700,000 immunization records, which might have told us why squalene was showing up in ...
Description: Squalene is a component of some adjuvants that is added to vaccines to enhance the immune response. A naturally occurring substance found in plants, animals and humans, squalene is synthesized in the liver and circulates in the human bloodstream. It is also found in a variety of foods, cosmetics, over-the-counter medications and health supplements.
Description: Squalene, a naturally occurring substance found in humans, animals and plants, is highly purified for the vaccine manufacturing process. FLUAD is approved for use among people 65 years and older, who often have a lower protective immune response after flu vaccination compared to younger, healthier people. Why are adjuvants added to flu vaccines?
Description: The most challenging aspect of assessment of adjuvant risk is determination of the basis of reported associations between use of vaccines containing specific adjuvants and development of rare autoimmune or chronic degenerative disorders—for example, associations between use of squalene emulsion–adjuvanted vaccines and narcolepsy or Gulf War ...
Description: Squalene is a naturally occurring oil which has been used in the development of vaccine adjuvants, such as the oil-in-water emulsion MF59. In past years, by use of noncontrolled and nonvalidated assays, a claim was made that antisqualene antibodies were detectable in the sera of individuals with the so-called Gulf War syndrome. Using a validated enzyme-linked immunosorbent assay for the ...
Description: Flu vaccines can also contain a number of chemical toxins, including ethylene glycol (antifreeze), formaldehyde, phenol (carbolic acid) and even antibiotics like Neomycin and streptomycin. In addition to the viruses and other additives, many vaccines also contain immune adjuvants like aluminum and squalene.
Description: An adjuvant like squalene can be used to stretch the availability of a vaccine, since adjuvant-supplemented vaccines are more effective and can thus be given in smaller doses.
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