Description: Spontaneous bacterial peritonitis (SBP) is the development of a bacterial infection in the peritoneum, despite the absence of an obvious source for the infection. It is specifically an infection of the ascitic fluid – an increased volume of peritoneal fluid. Ascites is most commonly a complication of cirrhosis of the liver. It can also occur in patients with nephrotic syndrome.
Description: Spontaneous bacterial peritonitis (SBP) is defined as an ascitic fluid infection without an evident intra-abdominal surgically treatable source . The presence of SBP, which almost always occurs in patients with cirrhosis and ascites, is suspected because of signs and symptoms such as fever, abdominal pain, or altered mental status .
Description: They will also provide recommendations for the management of spontaneous bacterial peritonitis (SBP) and hepatorenal syndrome, which often affect patients with cirrhosis. “It is estimated that almost 60 percent of cirrhotic patients develop ascites within 10 years of their disease, which is a huge proportion of patients.
Description: Risk factors. Patients with cirrhosis who are in a decompensated state are at the highest risk of developing spontaneous bacterial peritonitis.  Bacterial translocation (viable microorganism passage from the intestinal lumen to mesenteric lymph nodes) is a key factor in the development of spontaneous bacterial peritonitis.  Low complement levels are associated with the development of ...
Description: Approximately 20% of individuals with cirrhosis develop ascites, which is a major risk factor for spontaneous bacterial peritonitis. 1 One of the major causes of cirrhosis is chronic hepatitis C viral (HCV) infection, however, according to data from the United States Preventive Services Task Force published in JAMA, 2 direct evidence on the ...
Description: ascites, spontaneous bacterial peritonitis (SBP), and hepatorenal syndrome (HRS),1 it became obvious that all other complica-tions of decompensated cirrhosis had to be covered. Within this framework, a formal deﬁnition of decompensated cirrhosis was sought. The natural history of cirrhosis is characterised by a
Description: INTRODUCTION. Spontaneous bacterial peritonitis (SBP) is defined as an ascitic fluid infection without an evident intra-abdominal surgically treatable source .The presence of SBP, which almost always occurs in patients with cirrhosis and ascites, is suspected because of suggestive signs and symptoms, such as fever, abdominal pain, or altered mental status (), though some patients are ...
Description: Upper gastrointestinal bleeding (UGB) increases the risk of SBP and other infections during or immediately after the bleeding episode (first 5‐7 days), with an incidence ranging between 16% (compensated cirrhosis) and 66% (advanced cirrhosis). 4 Bacterial infections in this setting increase the probability of failure to control bleeding ...
Description: SBP is particularly common in ascites caused by hepatic cirrhosis. This infection can cause serious sequelae or death. The most common bacteria causing SBP are gram-negative Escherichia coli and Klebsiella pneumoniae and gram-positive Streptococcus pneumoniae; usually only a single organism is involved.
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