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Link: https://www.britannica.com/science/isocitrate
Description: In metabolism: Formation of coenzyme A, carbon dioxide, and reducing equivalent. …in such a way that isocitrate is formed.
Link: https://en.wikipedia.org/wiki/Isocitrate
Description: The isocitrate anion is a substrate of the citric acid cycle. Isocitrate is formed from citrate with the help of the enzyme aconitase, and is acted upon by isocitrate dehydrogenase . Isocitric acid is commonly used as a marker to detect the authenticity and quality of fruit products, most often citrus juices.
Link: https://medical-dictionary.thefreedictionary.com/isocitrate
Description: i·so·ci·trate. ( ī'sō-sit'rāt ), ( ī-sīt'rāt ), A salt or ester of isocitric acid. Farlex Partner Medical Dictionary © Farlex 2012.
Link: https://encyclopedia2.thefreedictionary.com/Isocitrate
Description: The product (ivosidenib) is an isocitrate dehydrogenase-1 (IDH1) inhibitor indicated in the United States as a treatment for acute myeloid leukaemia with a susceptible IDH1 mutation under the conditions where in patients with newly diagnosed IDH1-susceptible acute myeloid leukaemia who are up to 75 years old or have comorbidities that preclude the use of intensive induction chemotherapy and in ...
Link: http://www.chemspider.com/Chemical-Structure.4573809.html
Description: isocitrate. Molecular Formula C 6 H 5 O 7; Average mass 189.101 Da; Monoisotopic mass 189.005173 Da; ChemSpider ID 4573809
Link: https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase
Description: Isocitrate dehydrogenase and is an enzyme that catalyzes the oxidative decarboxylation of isocitrate, producing alpha-ketoglutarate and CO2. This is a two-step process, which involves oxidation of isocitrate to oxalosuccinate, followed by the decarboxylation of the carboxyl group beta to the ketone, forming alpha-ketoglutarate. In humans, IDH exists in three isoforms: IDH3 catalyzes the third step of the citric acid cycle while converting NAD+ to NADH in the mitochondria. The isoforms IDH1 and I
Link: https://www.sigmaaldrich.com/catalog/product/sigma/mak061
Description: Isocitrate is a TCA cycle intermediate that is formed from citrate by the activity of the enzyme aconitase. In the TCA cycle, isocitrate is oxidized by isocitrate dehydrogenase (IDH) to α-ketoglutarate with the generation of NAD(P)H. In plants and lower organisms, isocitrate is the branch point from which the glyoxylate shunt operates.
Link: https://pubchem.ncbi.nlm.nih.gov/compound/1-Hydroxypropane-1_2_3-tricarboxylate
Description: Isocitrate(3-) is propan-1-ol with a hydrogen at each of the 3 carbon positions substituted with a carboxylate group. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite.
Link: https://www.sciencedirect.com/topics/neuroscience/isocitrate-dehydrogenase
Description: Isocitrate dehydrogenase (IDH) is an enzyme that is best known from its role in the Krebs cycle, catalyzing the oxidative decarboxylation of isocitrate, resulting in alpha-ketoglutarate and carbon dioxide. The isoforms IDH1 and IDH2 encode a cytosolic and a mitochondrial protein, respectively.
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