Description: An adjuvant is an ingredient used in some vaccines that helps create a stronger immune response in people receiving the vaccine. In other words, adjuvants help vaccines work better. Some vaccines that are made from weakened or killed germs contain naturally occurring adjuvants and help the body produce a strong protective immune response.
Description: Pertussis vaccine is a vaccine that protects against whooping cough (pertussis). There are two main types: whole-cell vaccines and acellular vaccines. The whole-cell vaccine is about 78% effective while the acellular vaccine is 71–85% effective.
Description: About Diphtheria, Tetanus, and Pertussis Vaccines. ... Each 0.5 mL dose also contains 319 µg aluminum from aluminum salts used as adjuvants. Other ingredients per 0.5 mL dose include
Description: Improved pertussis vaccines based on adjuvants that induce cell-mediated immunity. Allen AC(1), Mills KH. ... Bordetella pertussis is a Gram-negative bacterium that causes the severe and sometimes lethal respiratory disease whooping cough in infants and children. There has been a recent resurgence in the number of cases of pertussis in several ...
Description: Key roles of adjuvants in modern vaccines. ... are not optimally induced by the most commonly used adjuvants in vaccines approved for human use, including alum and oil-in-water ... pertussis and ...
Description: A tetanus, diphtheria, and pertussis vaccine, for example, contains small quantities of inactivated toxins produced by each of the target bacteria, but also contains some aluminium hydroxide. Such aluminium salts are common adjuvants in vaccines sold in the United States and have been used in vaccines for more than 70 years. Mechanism
Description: Efforts to develop safe and effective vaccines increasingly involve the use of adjuvants—substances formulated as part of a vaccine to boost immune responses and enhance the vaccine’s effectiveness. NIAID supports a broad portfolio of vaccine adjuvant research, ranging from basic immunology studies to clinical testing of adjuvanted vaccine candidates.
Description: Vaccines also contain DNA, which is harvested from aborted infants. As adjuvants in vaccines, one hundred million bits and strands of human DNA are allowed per dose. When our cells die, they go through a process called apoptosis, which breaks down the DNA in the cell so that it is not released into the bloodstream.
Description: Collected resources and information for pertussis (whooping cough) disease and vaccination: Access the latest recommendations, news, information, and resources from IAC, government agencies, professional journals, and other organizations in one spot on immunize.org.
Description: Adjuvants were initially used in an empirical fashion to enhance the immune response to antigen, but became necessary components of many vaccines as purified antigens with lower immunogenicity were selected more and more frequently, as compared to live attenuated and whole-pathogen vaccine approaches.
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